First Blood Test to Diagnose Celiac Disease

Researchers have currently been able to identify biomarkers that may become the world’s first blood test to diagnose celiac disease. The scientists found that gluten intake in individuals with celiac disease led to an upsurge in some inflammatory molecules in the bloodstream that is commonly associated with some signs.
The procedure for detecting celiac disease is quite long and tasking, sometimes running from weeks to months. Current diagnosis for celiac disease involves eating gluten and putting up with the side effects. Celiac disease is a lifetime ailment that affects about 1% of people in Western countries. The immune system of people with celiac disease reacts negatively when gluten is consumed. Gluten is a protein found in barely, wheat, rye, and foods that contain them.
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Now, researchers have discovered a blood test that could only take a few hours, instead of weeks and months of consuming gluten.
The novel research, which was published in the journal Science Advances, was headed by the biotechnology firm ImmusanT Inc., of Cambridge, MA.
According to co- author Dr. Robert P. Anderson, Chief Scientific Officer of ImmusanT;
“we have described for the first time, the inflammatory reaction that those with celiac disease experience hours after they are have eaten gluten.”
Dr. Anderson added that this new discovery has open ways for other approaches that that can help people without celiac disease, but with close signs, for a more proper treatment.
First blood test to diagnose celiac disease – Highlights from the study
The team of researchers injected gluten peptides into people with celiac disease. This led to onset of adverse symptoms.
Dr. Anderson explained that the hostile symptoms linked with the disease are connected to a rise in inflammatory molecules in the bloodstream. This reaction is akin to what occurs when an infection is present. But gluten is the triggering factor for people with celiac disease.
Researchers at ImmusanT identified the molecules during a trial of a prospective celiac treatment. They discovered that injecting gluten peptides led to symptoms that linked with raised levels of the blood markers.
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The research team is currently working on a simple blood test to diagnose celiac disease using the discovery.
Gluten in gut
When persons with celiac disease ingests gluten foods, it prompts the immune system to carry out an attack on the small intestine, hence damaging the digestive system and reducing its capability of absorbing nutrients. This can lead to symptoms like diarrhea, weight loss, bloating, vomiting, anemia, and visible fats in stools.
To avoid these unpleasant symptoms, people diagnosed with celiac disease have to be on gluten-free diet for life.
Wrapping Up
For people on a celiac free diet who having been properly diagnosed with celiac disease, instead of consuming these diet for weeks to months, it may only entail consuming a small gluten meal and taking a blood test before, and 4 hours after the meal.


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